This letter is regarding the article by Grant et al. entitled “Solid Cancer Incidence among the Life Span Study of Atomic Bomb Survivors: 1958–2009” published in Radiation Research (1 ). This article describes the findings of the third analysis of solid cancer incidence among the Life Span Study (LSS) cohort of atomic bomb survivors in Hiroshima and Nagasaki. In this publication, which includes an additional 11 years of follow-up since the previous reported analysis, Grant et al. report a linear dose-response relationship for cancer incidence in females and a linear-quadratic one for males. The authors also claim that they found a linear increase in excess relative risk (ERR) for dose range as low as 0–100 mGy. Although the paper addresses a very challenging issue, it has some major shortcomings.
One concern regarding the results presented in this article is that solid cancer incidence rate presented in Table...