Comments on “Cellular Therapies for Treatment of Radiation Injury after a Mass Casualty Incident” (Radiat Res 2017; 188:242-45)

It was with a great interest that we have read the articles “Cellular Therapies for Treatment of Radiation Injuries after a Mass Casualty Incident”¹  by C. Rios, J. R. Jourdain and A. L. DiCarlo and Workshop Report “Cellular Therapies for Treatment of Radiation Injury: Report from a NIH/NIAID and IRSN Workshop“ by DiCarlo et al. Indeed, there is, from our point of view too, a great need in animal model development to overcome the current limits in the use of mesenchymal stromal/stem cells (MSCs) to mitigate radiation damages at the level of numerous tissues, especially cutaneous and muscular. One of them is the low efficacy, if any depending of the targeted tissue, of unmatched MSCs from banking that could be the first line of defense in a (military) mass casualty scenario (Percy military hospital and Centre de Transfusion sanguine des Armées). As an example, our group was unable...