X-irradiation induces dysplasia of hair in the growing phase by two different mechanisms: The first and more radiosensitive can be greatly influenced by oxygen; the second, more radioresistant, is slightly or not sensitive to anoxia. Cystamine administered before irradiation by intraperitoneal injection acts on the hair bulb in two ways-for lower doses indirectly by anoxia and for stronger doses by its own mode of action. Cysteamine and, even more, cystamine injected after irradiation exercise a definite dysplasing action which enhances that of the X-rays.

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