Many of the dividing normal tissues in the mammalian organism retain a great capacity of recovery after depopulation by, for example, ionizing radiations. The pattern of recovery, however, differs greatly from tissue to tissue, and the analysis of these recovery patterns may give useful information on the cellular kinetics of the tissues concerned, information which may be exploited in radiotherapy. There are still very few normal tissues which can be quantitatively studied from the point of view of cell population kinetics. The two types of tissues perhaps best understood are the intestinal epithelium and the hemopoietic system. The kinetics of these two systems will be discussed, together with the current models of these cell populations, and the perturbations caused by ionzing radiations will be analyzed.
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L. G. Lajtha; Radiation Effects on Steady-State Cell Populations. Radiat Res 1 March 1968; 33 (3): 659–669. doi: https://doi.org/10.2307/3572421
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