Mice from three strains (ICR, C57Bl/6J, and Bagg-Swiss) were exposed to neutrons at 6, 8, 12, or 16 weeks of age. Strain, as well as age, was found to influence the radiation response as measured by median lethal dose and survival time. ICR strain mice were irradiated under similar conditions at dose rates of 1, 10, 50, 100, or 200 rads/min or a pulse of radiation. There was no demonstrable effect of exposure intensity on median lethal dose or on survival time.
The Effect of Age, Strain, and Exposure Intensity on the Mortality Response of Neutron-Irradiated Mice
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Dan Hightower, Kent T. Woodward, Mary M. McLaughlin, Fletcher F. Hahn; The Effect of Age, Strain, and Exposure Intensity on the Mortality Response of Neutron-Irradiated Mice. Radiat Res 1 August 1968; 35 (2): 369–377. doi: https://doi.org/10.2307/3572383
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