Inflorescences of Tradescantia paludosa were treated with 5-fluorodeoxyuridine (FUdR) to test the effects of this compound on radiation-induced chromatid aberrations. Treatment with 10-6 M FUdR during G2 significantly reduced the chromatid exchange frequency but had no effect on the chromatid or isochromatid breaks. Treatment during S disturbed all three of the aberration frequencies and caused a 15-hour delay in the appearance of chromosome aberrations. When inflorescences were allowed to recover in water after FUdR treatment and before irradiation, the effects on the chromatid and isochromatid breaks were abolished with a 1 1/2-hour recovery period while the exchange frequency returned to the control level after 3 hours in water.
Skip Nav Destination
Research Article| May 01 1969
The Effects of 5-Fluorodeoxyuridine on Radiation-Induced Chromatid Aberrations in Tradescantia Microspores
Radiat Res (1969) 38 (2): 404–413.
- Views Icon Views
- Share Icon Share
- Search Site
Priscilla Strickland Rushton; The Effects of 5-Fluorodeoxyuridine on Radiation-Induced Chromatid Aberrations in Tradescantia Microspores. Radiat Res 1 May 1969; 38 (2): 404–413. doi: https://doi.org/10.2307/3572782
Download citation file:
Citing articles via
Commonalities Between COVID-19 and Radiation Injury
Carmen I. Rios, David R. Cassatt, Brynn A. Hollingsworth, Merriline M. Satyamitra, Yeabsera S. Tadesse, Lanyn P. Taliaferro, Thomas A. Winters, Andrea L. DiCarlo
Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks?
Pataje G. Prasanna, Gayle E. Woloschak, Andrea L. DiCarlo, Jeffrey C. Buchsbaum, Dörthe Schaue, Arnab Chakravarti, Francis A. Cucinotta, Silvia C. Formenti, Chandan Guha, Dale J. Hu, Mohammad K. Khan, David G. Kirsch, Sunil Krishnan, Wolfgang W. Leitner, Brian Marples, William McBride, Minesh P. Mehta, Shahin Rafii, Elad Sharon, Julie M. Sullivan, Ralph R. Weichselbaum, Mansoor M. Ahmed, Bhadrasain Vikram, C. Norman Coleman, Kathryn D. Held
Germicidal Efficacy and Mammalian Skin Safety of 222-nm UV Light
Manuela Buonanno, Brian Ponnaiya, David Welch, Milda Stanislauskas, Gerhard Randers-Pehrson, Lubomir Smilenov, Franklin D. Lowy, David M. Owens, David J. Brenner