Few data exist on the uptake in mammalian tissues of14 C inspired as14 CO2. The effects of this uptake are largely a matter of speculation. Mice were exposed for long periods in a special respiratory chamber to concentrations of the radioactive gas ranging from about 20 times below the maximum permissible concentration to over 100 times above. Maximum uptake was obtained after 30 days of exposure. The uptake as measured in disintegrations per minute increased at the highest concentration to over 1000 times background. Histologic study revealed no pathologic effects ascribable either to radiation or transmutation.

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