Postnatal behavior as measured by activity and elimination in the open field, activity in exercise wheels, and hoarding performance, was followed in mice of the ENA strain that had been exposed to 300 R on the day of birth. Long-lasting effects of neonatal irradiation were evidenced by changes in several characteristics. Irradiated mice weighed only 87% as much as controls at 7 weeks of age. Neonatal irradiation was found to decrease elimination scores, activity in wheels, and hoarding scores, but was not found to have a significant effect on open-field activity. Additional studies examined the relationship between locomotion in the open field and different levels of neonatal irradiation in three genotypes of mice. In general, locomotion was observed to decrease with increasing levels of irradiation in the three genotypes, with all three genotypes showing a marked decrease after receiving 300 R. Comparison of present results with those of other studies has demonstrated that strain differences may influence the type of behavioral response observed after neonatal irradiation.
Skip Nav Destination
Research Article| March 01 1970
Neonatal Irradiation and Postnatal Behavior in Mice
Donald J. Nash ;
Arnold Napoleon ;
Radiat Res (1970) 41 (3): 594–601.
- Views Icon Views
- Share Icon Share
- Search Site
Donald J. Nash, Arnold Napoleon, Le Etta Sprackling; Neonatal Irradiation and Postnatal Behavior in Mice. Radiat Res 1 March 1970; 41 (3): 594–601. doi: https://doi.org/10.2307/3572846
Download citation file:
Citing articles via
Commonalities Between COVID-19 and Radiation Injury
Carmen I. Rios, David R. Cassatt, Brynn A. Hollingsworth, Merriline M. Satyamitra, Yeabsera S. Tadesse, Lanyn P. Taliaferro, Thomas A. Winters, Andrea L. DiCarlo
Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks?
Pataje G. Prasanna, Gayle E. Woloschak, Andrea L. DiCarlo, Jeffrey C. Buchsbaum, Dörthe Schaue, Arnab Chakravarti, Francis A. Cucinotta, Silvia C. Formenti, Chandan Guha, Dale J. Hu, Mohammad K. Khan, David G. Kirsch, Sunil Krishnan, Wolfgang W. Leitner, Brian Marples, William McBride, Minesh P. Mehta, Shahin Rafii, Elad Sharon, Julie M. Sullivan, Ralph R. Weichselbaum, Mansoor M. Ahmed, Bhadrasain Vikram, C. Norman Coleman, Kathryn D. Held
Germicidal Efficacy and Mammalian Skin Safety of 222-nm UV Light
Manuela Buonanno, Brian Ponnaiya, David Welch, Milda Stanislauskas, Gerhard Randers-Pehrson, Lubomir Smilenov, Franklin D. Lowy, David M. Owens, David J. Brenner
Photon GRID Radiation Therapy: A Physics and Dosimetry White Paper from the Radiosurgery Society (RSS) GRID/LATTICE, Microbeam and FLASH Radiotherapy Working Group
Hualin Zhang, Xiaodong Wu, Xin Zhang, Sha X. Chang, Ali Megooni, Eric D. Donnelly, Mansoor M. Ahmed, Robert J. Griffin, James S. Welsh, Charles B. Simone, II, Nina A. Mayr