Osborne-Mendel rats irradiated on one of Days 17, 19, or 21 of gestation with 196 R exhibited significantly more bar press escape/avoidance responses as a function of increasing shock intensity than did sham-irradiated controls. In a two-bar punishment paradigm irradiated rats initiated significantly fewer shock-on periods and made a greater number of responses during time-out as compared with time-in periods as a function of increased shock intensity.

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