The effects of60 Co gamma radiation on the production of the red nonessential tripyrrole pigment, prodigiosin, have been studied in Serratia marcescens. A comparison of the survival of pigmenting and nonpigmenting strains of S. marcescens has been carried out. Wild-type S. marcescens, Nima, which synthesizes prodigiosin, and three nonpigmenting mutant strains were examined. Measurement of colony-forming ability after gamma radiation is always greater in nonpigmenting (white) mutants of S. marcescens than in pigmenting strains. The red pigment may be acting as an endogenous radiosensitizer.
Effect of Gamma Radiation on Serratia marcescens. Studies on the Radiosensitivity of Prodigiosin Production
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William T. Bartlett, Gerard A. O'Donovan, Richard D. Neff; Effect of Gamma Radiation on Serratia marcescens. Studies on the Radiosensitivity of Prodigiosin Production. Radiat Res 1 July 1970; 43 (1): 196–203. doi: https://doi.org/10.2307/3572870
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