The physiological parameters needed for estimating the activity of tritium taken into the body from various tritiated environments are well established experimentally. Less certain is the relation of dose equivalent rate to body burden. A quality factor of unity appears reasonable. For chronic exposures to tritium, isotopic concentrations effects and transmutation effects are unimportant. The choice of body water as the critical organ is conservative since no tissue has a higher proportion of hydrogen. Recommended limiting levels for tritium in drinking water, in air, and in food are also conservative. For acute exposures, the main problem is estimating the dose equivalent from tritium bound to tissue components. One general analysis suggests an upper limit for this of 25% of the dose equivalent from tritium in body water.
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R. V. Osborne; Permissible Levels of Tritium in Man and the Environment. Radiat Res 1 April 1972; 50 (1): 197–211. doi: https://doi.org/10.2307/3573479
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