The biological half-life of tritium was measured in the body water and in brain, liver, lung, kidney, heart and muscle tissues of two groups of kangaroo rats captured in the tritiated environment at Sedan Crater in the Nevada Test Site. These animals had been exposed to tritium in their natural food for their entire lifetime. The rodents were maintained on tritium-free food in the laboratory during the two study periods of five and nine months. At regular intervals, several animals from each group were killed, dissected and lyophilized. Tritium in the body water was determined by liquid scintillation counting. Dried tissue residues were assayed by sealed-flask combustion and liquid scintillation counting. The biological half-life of tritium in the tissue compartment of these uniquely exposed animals was 1.5 to 4 times that of the body water. At the time of trapping, a slight enrichment of tritium in tissue was indicated by the initial ratio of tissue to body water tritium which ranged from 1.2 to 1.6 with an average value of 1.40 ± 0.14.
Skip Nav Destination
Research Article| May 01 1972
Biological Half-Life Studies of Tritium in Chronically Exposed Kangaroo Rats
Radiat Res (1972) 50 (2): 426–440.
- Views Icon Views
- Share Icon Share
- Search Site
J. R. Martin, J. J. Koranda; Biological Half-Life Studies of Tritium in Chronically Exposed Kangaroo Rats. Radiat Res 1 May 1972; 50 (2): 426–440. doi: https://doi.org/10.2307/3573500
Download citation file:
Citing articles via
Commonalities Between COVID-19 and Radiation Injury
Carmen I. Rios, David R. Cassatt, Brynn A. Hollingsworth, Merriline M. Satyamitra, Yeabsera S. Tadesse, Lanyn P. Taliaferro, Thomas A. Winters, Andrea L. DiCarlo
Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks?
Pataje G. Prasanna, Gayle E. Woloschak, Andrea L. DiCarlo, Jeffrey C. Buchsbaum, Dörthe Schaue, Arnab Chakravarti, Francis A. Cucinotta, Silvia C. Formenti, Chandan Guha, Dale J. Hu, Mohammad K. Khan, David G. Kirsch, Sunil Krishnan, Wolfgang W. Leitner, Brian Marples, William McBride, Minesh P. Mehta, Shahin Rafii, Elad Sharon, Julie M. Sullivan, Ralph R. Weichselbaum, Mansoor M. Ahmed, Bhadrasain Vikram, C. Norman Coleman, Kathryn D. Held
Germicidal Efficacy and Mammalian Skin Safety of 222-nm UV Light
Manuela Buonanno, Brian Ponnaiya, David Welch, Milda Stanislauskas, Gerhard Randers-Pehrson, Lubomir Smilenov, Franklin D. Lowy, David M. Owens, David J. Brenner