Mature pigs were given 100, 200, 300, or 400 R (midline in air) exposures to gamma radiation at 50 R/min. Leukocyte cultures established from postirradiation blood and from samples simultaneously irradiated in vitro were evaluated at intervals up to 96 h in culture. White cell counts, the proportion of lymphocytes recovered, and the proportion of viable cells were reduced by irradiation, but not in a dose-related manner. The effects on labeling and mitotic indexes, polyploid rates, and nuclear volume increases were dose dependent. While considerable variability among animals existed, there was a close relationship between the in vivo and in vitro responses of their leukocytes.
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Research Article| November 01 1972
Behavior of Swine Leukocytes in Culture after In Vivo or In Vitro Gamma Irradiation
M. W. Banner ;
Radiat Res (1972) 52 (2): 301–308.
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A. F. McFee, M. W. Banner, Mary N. Sherrill; Behavior of Swine Leukocytes in Culture after In Vivo or In Vitro Gamma Irradiation. Radiat Res 1 November 1972; 52 (2): 301–308. doi: https://doi.org/10.2307/3573569
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