X-Irradiation delays division of heat-synchronized Tetrahymena pyriformis (a ciliate protozoon) if exposure occurs prior to a critical time after the end of the synchronizing treatment (EST). Exposure after this critical time does not significantly delay the first synchronized division but does delay the second. The time of the transition from a state where the cells are delayed to one where they are not is somewhat dose dependent: within limits, the larger the exposure, the later is the transition time. The division delay response is always correlated with a resorption of the oral primordium of the presumptive posterior daughter cell. The amount of time for resorption varies with the time after EST at which the cells are irradiated and is dose dependent. The data are consistent with the hypothesis that irradiation produces damage during all parts of the synchronized cell cycle, but that, depending on the dose and the time of irradiation after EST, the damage may or may not trigger a response that leads to delay of the first division.
Skip Nav Destination
Research Article| December 01 1972
X-Ray-Induced Delay of Cell Division in Synchronized Tetrahymena pyriformis
Radiat Res (1972) 52 (3): 603–617.
- Views Icon Views
- Share Icon Share
- Search Site
F. A. Hodge, D. S. Nachtwey; X-Ray-Induced Delay of Cell Division in Synchronized Tetrahymena pyriformis. Radiat Res 1 December 1972; 52 (3): 603–617. doi: https://doi.org/10.2307/3573518
Download citation file:
Citing articles via
Commonalities Between COVID-19 and Radiation Injury
Carmen I. Rios, David R. Cassatt, Brynn A. Hollingsworth, Merriline M. Satyamitra, Yeabsera S. Tadesse, Lanyn P. Taliaferro, Thomas A. Winters, Andrea L. DiCarlo
Monte Carlo Simulation of SARS-CoV-2 Radiation-Induced Inactivation for Vaccine Development
Ziad Francis, Sebastien Incerti, Sara A. Zein, Nathanael Lampe, Carlos A. Guzman, Marco Durante
Low-Dose Radiation Therapy (LDRT) for COVID-19: Benefits or Risks?
Pataje G. Prasanna, Gayle E. Woloschak, Andrea L. DiCarlo, Jeffrey C. Buchsbaum, Dörthe Schaue, Arnab Chakravarti, Francis A. Cucinotta, Silvia C. Formenti, Chandan Guha, Dale J. Hu, Mohammad K. Khan, David G. Kirsch, Sunil Krishnan, Wolfgang W. Leitner, Brian Marples, William McBride, Minesh P. Mehta, Shahin Rafii, Elad Sharon, Julie M. Sullivan, Ralph R. Weichselbaum, Mansoor M. Ahmed, Bhadrasain Vikram, C. Norman Coleman, Kathryn D. Held
Germicidal Efficacy and Mammalian Skin Safety of 222-nm UV Light
Manuela Buonanno, Brian Ponnaiya, David Welch, Milda Stanislauskas, Gerhard Randers-Pehrson, Lubomir Smilenov, Franklin D. Lowy, David M. Owens, David J. Brenner
RITCARD: Radiation-Induced Tracks, Chromosome Aberrations, Repair and Damage
Ianik Plante, Artem Ponomarev, Zarana Patel, Tony Slaba, Megumi Hada