NEDH rats usually have a low (1%) incidence of leukemia, chiefly myeloid in type. This is slightly increased (5%) by parabiosis, especially in females. A dose of 1000 R of x-radiation to one of the pair lowers the incidence of leukemia, but not to usual spontaneous levels. Leukemia may develop in only one of the parabiont pair, which, due to the intimate relationship of the two, would be unlikely to occur if the disease were virus induced.
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Research Article| January 01 1974
Leukemia in Irradiated Parabiotic Rats
Shields Warren ;
Radiat Res (1974) 57 (1): 67–72.
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Shields Warren, K. B. Udupa, R. N. Chute; Leukemia in Irradiated Parabiotic Rats. Radiat Res 1 January 1974; 57 (1): 67–72. doi: https://doi.org/10.2307/3573756
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