It is well established that at a given level of cell survival fractionation reduces the effect of low LET radiation more than that of high LET radiation. However, theoretical considerations indicate that at a given absorbed dose fractionation should result in an increase of cell survival by a factor that is substantially independent of radiation quality. Experimental data confirm this expectation.
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Harald H. Rossi; A Note on the Effects of Fractionation of High LET Radiations. Radiat Res 1 April 1976; 66 (1): 170–173. doi: https://doi.org/10.2307/3574365
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