Hyperthermia (41°C for 1 hr) before or after irradiation of plateau phase V79 Chinese hamster cells potentiated radiation effect. This effect was characterized primarily by a decreased width of the survival curve. However, the repair of potentially lethal or sublethal damage was not suppressed by preirradiation hyperthermia. It is suggested that hyperthermic potentiation of radiation effect in plateau phase cells may not depend upon inhibition of damage repair.

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