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Marc S. Mendonca
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Journal Articles

The Role of Natural Background Radiation in Maintaining Genomic Stability in the CGL1 Human Hybrid Model System

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Jake Pirkkanen, Taylor Laframboise, Jayden Peterson, Alyssa Labelle, Forest Mahoney ...
Journal: Radiation Research
Radiat Res (2024) 202 (4): 617–625.
https://doi.org/10.1667/RADE-23-00243.1
Published: 08 October 2024
View articletitled, The Role of Natural Background Radiation in Maintaining Genomic Stability in the CGL1 Human Hybrid Model System
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Journal Articles

“Lethal Mutations” a Misnomer or the Start of a Scientific Revolution?

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Carmel Mothersill, Rhea Desai, Colin B. Seymour, Marc S. Mendonca
Journal: Radiation Research
Radiat Res (2024) 202 (2): 205–214.
https://doi.org/10.1667/RADE-24-00018.1
Published: 26 June 2024
View articletitled, “Lethal Mutations” a Misnomer or the Start of a Scientific Revolution?
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Includes: Supplementary data
Journal Articles

Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo

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Jake Pirkkanen, Sujeenthar Tharmalingam, Christopher Thome, Helen Chin Sinex, Laura V. Benjamin ...
Journal: Radiation Research
Radiat Res (2023) 200 (1): 48–64.
https://doi.org/10.1667/RADE-22-00216.1
Published: 21 April 2023
View articletitled, Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo
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Journal Articles

The REPAIR Project, a Deep-Underground Radiobiology Experiment Investigating the Biological Effects of Natural Background Radiation: The First 6 Years

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Jake Pirkkanen, Christine Lalonde, Michel Lapointe, Taylor Laframboise, Marc S. Mendonca ...
Journal: Radiation Research
Radiat Res (2023) 199 (3): 290–293.
https://doi.org/10.1667/RADE-22-00193.1
Published: 06 February 2023
View articletitled, The REPAIR Project, a Deep-Underground Radiobiology Experiment Investigating the Biological Effects of Natural Background Radiation: The First 6 Years
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Journal Articles

The Protective Effect of Estrogen Against Radiation Cataractogenesis is Dependent Upon the Type of Radiation

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Joy Garrett, Shailaja Valluri, Marc S. Mendonca, Robert M. Bigsby, Jennifer Lopez ...
Journal: Radiation Research
Radiat Res (2020) 194 (5): 557–565.
https://doi.org/10.1667/RADE-20-00015.1
Published: 12 October 2020
View articletitled, The Protective Effect of Estrogen Against Radiation Cataractogenesis is Dependent Upon the Type of Radiation
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Journal Articles

In Vitro Cell-free DNA Quantification: A Novel Method to Accurately Quantify Cell Survival after Irradiation

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Christopher R. Deig, Rachel T. Thowe, Elizabeth D. Frye, Helen J. Chin-Sinex, Marc S. Mendonca ...
Journal: Radiation Research
Radiat Res (2018) 190 (1): 22–27.
https://doi.org/10.1667/RR15016.1
Published: 29 May 2018
View articletitled, In Vitro Cell-free DNA Quantification: A Novel Method to Accurately Quantify Cell Survival after Irradiation
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Includes: Supplementary data
Journal Articles

The CGL1 (HeLa × Normal Skin Fibroblast) Human Hybrid Cell Line: A History of Ionizing Radiation Induced Effects on Neoplastic Transformation and Novel Future Directions in SNOLAB

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Jake S. Pirkkanen, Douglas R. Boreham, Marc S. Mendonca
Journal: Radiation Research
Radiat Res (2017) 188 (4.2): 512–524.
https://doi.org/10.1667/RR14911.1
Published: 05 September 2017
View articletitled, The CGL1 (HeLa × Normal Skin Fibroblast) Human Hybrid Cell Line: A History of Ionizing Radiation Induced Effects on Neoplastic Transformation and Novel Future Directions in SNOLAB
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Journal Articles

Radiation-Induced Fibrosis: Mechanisms and Opportunities to Mitigate. Report of an NCI Workshop, September 19, 2016.

Open Access
Deborah E. Citrin, Pataje G. S. Prasanna, Amanda J. Walker, Michael L. Freeman, Iris Eke ...
Journal: Radiation Research
Radiat Res (2017) 188 (1): 1–20.
https://doi.org/10.1667/RR14784.1
Published: 10 May 2017
View articletitled, Radiation-Induced Fibrosis: Mechanisms and Opportunities to Mitigate. Report of an NCI Workshop, September 19, 2016.
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Journal Articles

Further Characterization of the Mitigation of Radiation Lethality by Protective Wounding

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Joseph R. Dynlacht, Joy Garrett, Rebecca Joel, Katharina Lane, Marc S. Mendonca ...
Journal: Radiation Research
Radiat Res (2017) 187 (6): 732–742.
https://doi.org/10.1667/RR14725.1
Published: 24 April 2017
View articletitled, Further Characterization of the Mitigation of Radiation Lethality by Protective Wounding
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Journal Articles

Blood-Based Nucleic Acid Biomarkers as a Potential Tool to Determine Radiation Therapy Response in Non-Small Cell Lung Cancer

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Christopher R. Deig, Marc S. Mendonca, Tim Lautenschlaeger
Journal: Radiation Research
Radiat Res (2017) 187 (3): 333–338.
https://doi.org/10.1667/RR14613.1
Published: 10 February 2017
View articletitled, Blood-Based Nucleic Acid Biomarkers as a Potential Tool to Determine Radiation Therapy Response in Non-Small Cell Lung Cancer
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Journal Articles

Radiosensitizing Pancreatic Cancer Xenografts by an Implantable Micro-Oxygen Generator

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Ning Cao, Seung Hyun Song, Teimour Maleki, Michael Shaffer, Keith M. Stantz ...
Journal: Radiation Research
Radiat Res (2016) 185 (4): 431–437.
https://doi.org/10.1667/RR14149.1
Published: 22 March 2016
View articletitled, Radiosensitizing Pancreatic Cancer Xenografts by an Implantable Micro-Oxygen Generator
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Includes: Supplementary data
Journal Articles

Subcutaneous Wounding Postirradiation Reduces Radiation Lethality in Mice

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Joy Garrett, Christie M. Orschell, Marc S. Mendonca, Robert M. Bigsby, Joseph R. Dynlacht
Journal: Radiation Research
Radiat Res (2014) 181 (6): 578–583.
https://doi.org/10.1667/RR13267.1
Published: 08 May 2014
View articletitled, Subcutaneous Wounding Postirradiation Reduces Radiation Lethality in Mice
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Journal Articles

Variations in the RBE for Cell Killing Along the Depth-Dose Profile of a Modulated Proton Therapy Beam

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Richard. A. Britten, Vahagn Nazaryan, Leslie K. Davis, Susan B. Klein, Dmitri Nichiporov ...
Journal: Radiation Research
Radiat Res (2012) 179 (1): 21–28.
https://doi.org/10.1667/RR2737.1
Published: 13 November 2012
View articletitled, Variations in the RBE for Cell Killing Along the Depth-Dose Profile of a Modulated Proton Therapy Beam
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Journal Articles

Differential Mechanisms of X-Ray-Induced Cell Death in Human Endothelial Progenitor Cells Isolated from Cord Blood and Adults

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Marc S. Mendonca, Helen Chin-Sinex, Ryan Dhaemers, Laura E. Mead, Merv C. Yoder ...
Journal: Radiation Research
Radiat Res (2011) 176 (2): 208–216.
https://doi.org/10.1667/RR2427.1
Published: 10 June 2011
View articletitled, Differential Mechanisms of X-Ray-Induced Cell Death in Human Endothelial Progenitor Cells Isolated from Cord Blood and Adults
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Journal Articles

Age and Hormonal Status as Determinants of Cataractogenesis Induced by Ionizing Radiation. I. Densely Ionizing (High-LET) Radiation

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Joseph R. Dynlacht, Shailaja Valluri, Joy Garrett, Marc S. Mendonca, Jennifer T. Lopez ...
Journal: Radiation Research
Radiat Res (2010) 175 (1): 37–43.
https://doi.org/10.1667/RR2319.1
Published: 10 November 2010
View articletitled, Age and Hormonal Status as Determinants of Cataractogenesis Induced by Ionizing Radiation. I. Densely Ionizing (High-LET) Radiation
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Journal Articles

Effects of Estrogen and Gender on Cataractogenesis Induced by High-LET Radiation

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Mark A. Henderson, Shailaja Valluri, Joy Garrett, Jennifer T. Lopez, Andrea Caperell-Grant ...
Journal: Radiation Research
Radiat Res (2010) 173 (2): 191–196.
https://doi.org/10.1667/RR1917.1
Published: 01 February 2010
View articletitled, Effects of Estrogen and Gender on Cataractogenesis Induced by High-LET Radiation
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Includes: Supplementary data
Journal Articles

Effect of Gender on Radiation-Induced Cataractogenesis

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Mark A. Henderson, Shailaja Valluri, Colleen DesRosiers, Jennifer T. Lopez, Christopher N. Batuello ...
Journal: Radiation Research
Radiat Res (2009) 172 (1): 129–133.
https://doi.org/10.1667/RR1589.1
Published: 01 July 2009
View articletitled, Effect of Gender on Radiation-Induced Cataractogenesis
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Journal Articles

Suppression of NF-κB Activity by Parthenolide Induces X-Ray Sensitivity through Inhibition of Split-Dose Repair in TP53 Null Prostate Cancer Cells

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Christopher Watson, Douglas A. Miller, Helen Chin-Sinex, Adam Losch, William Hughes ...
Journal: Radiation Research
Radiat Res (2009) 171 (4): 389–396.
https://doi.org/10.1667/RR1394.1
Published: 01 April 2009
View articletitled, Suppression of NF-κB Activity by Parthenolide Induces X-Ray Sensitivity through Inhibition of Split-Dose Repair in TP53 Null Prostate Cancer Cells
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Journal Articles

Estrogen Protects against Radiation-Induced Cataractogenesis

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Joseph R. Dynlacht, Shailaja Valluri, Jennifer Lopez, Falon Greer, Colleen DesRosiers ...
Journal: Radiation Research
Radiat Res (2008) 170 (6): 758–764.
https://doi.org/10.1667/RR1416.1
Published: 01 December 2008
View articletitled, Estrogen Protects against Radiation-Induced Cataractogenesis
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Journal Articles

Parthenolide Sensitizes Cells to X-Ray-Induced Cell Killing through Inhibition of NF-κB and Split-Dose Repair

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Marc S. Mendonca, Helen Chin-Sinex, Jaime Gomez-Millan, Nicholas Datzman, Michael Hardacre ...
Journal: Radiation Research
Radiat Res (2007) 168 (6): 689–697.
https://doi.org/10.1667/RR1128.1
Published: 01 December 2007
View articletitled, Parthenolide Sensitizes Cells to X-Ray-Induced Cell Killing through Inhibition of NF-κB and Split-Dose Repair
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