Background: Individuals living with cerebral palsy (CP) or spina bifida (SB) are at heightened risk for chronic health conditions that may develop or be influenced by the impairment and/or the process of aging. Objectives: The objective of this study was to compare the incidence of and adjusted hazards for musculoskeletal (MSK) morbidities among adults living with and without CP or SB. Methods: A retrospective, longitudinal cohort study was conducted among adults living with (n = 15,302) CP or SB and without (n = 1,935,480) CP or SB. Incidence estimates of common MSK morbidities were compared at 4 years of enrollment. Survival models were used to quantify unadjusted and adjusted hazard ratios for incident MSK morbidities. The analyses were performed in 2019 to 2020. Results: Adults living with CP or SB had a higher 4-year incidence of any MSK morbidity (55.3% vs. 39.0%) as compared to adults without CP or SB, and differences were to a clinically meaningful extent. Fully adjusted survival models demonstrated that adults with CP or SB had a greater hazard for all MSK disorders; this ranged from hazard ratio (HR) 1.40 (95% CI, 1.33 to 1.48) for myalgia to HR 3.23 (95% CI, 3.09 to 3.38) for sarcopenia and weakness. Conclusion: Adults with CP or SB have a significantly higher incidence of and risk for common MSK morbidities as compared to adults without CP or SB. Efforts are needed to facilitate the development of improved clinical screening algorithms and early interventions to reduce risk of MSK disease onset/progression in these higher risk populations.
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Summer 2022
Research Article|
August 17 2022
Musculoskeletal Morbidity Among Adults Living With Spina Bifida and Cerebral Palsy Available to Purchase
Heidi J. Haapala, MD;
Heidi J. Haapala, MD
*
1Department of Physical Medicine and Rehabilitation, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
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Mary Schmidt, DO;
Mary Schmidt, DO
*
1Department of Physical Medicine and Rehabilitation, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
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Paul Lin, MS;
Paul Lin, MS
2Institute for Healthcare Policy and Innovation, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
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Neil Kamdar, MA;
Neil Kamdar, MA
2Institute for Healthcare Policy and Innovation, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
3Department of Obstetrics and Gynecology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
4Department of Emergency Medicine, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
5Department of Surgery, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
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Elham Mahmoudi, PhD;
Elham Mahmoudi, PhD
2Institute for Healthcare Policy and Innovation, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
6Department of Family Medicine, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
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Mark D. Peterson, PhD
1Department of Physical Medicine and Rehabilitation, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
2Institute for Healthcare Policy and Innovation, Michigan Medicine, University of Michigan, Ann Arbor, Michigan
Corresponding author: Mark D. Peterson, PhD, MS, FACSM, Charles E. Lytle, Jr. Research Professor, Department of Physical Medicine and Rehabilitation, University of Michigan Medicine, 325 E. Eisenhower Parkway, Suite 2, Ann Arbor, Michigan 48108; phone: 734-763-0692; email: [email protected]
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Top Spinal Cord Inj Rehabil (2022) 28 (3): 73–84.
Citation
Heidi J. Haapala, Mary Schmidt, Paul Lin, Neil Kamdar, Elham Mahmoudi, Mark D. Peterson; Musculoskeletal Morbidity Among Adults Living With Spina Bifida and Cerebral Palsy. Top Spinal Cord Inj Rehabil 1 June 2022; 28 (3): 73–84. doi: https://doi.org/10.46292/sci21-00078
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