Preserving and maintaining bone mass after a spinal cord injury (SCI) is crucial to decrease the risk of fragility or low trauma fractures — significant health events that occur as a result of minimal trauma such as falling during transfers or from a standing height or less. There is an increased risk for low trauma fractures after an SCI especially in the lower extremity. Therefore, the purpose of this systematic review was to appraise the literature to provide clinical guidance for the optimization of bone health after SCI. The key research questions focused on prevention of acute bone loss after SCI (<1 year) and effective treatment of established low bone mass with long-standing SCI (⩾ 1 year). We report moderate evidence for the treatment of bone loss using pharmacology; however, nonpharmacological evidence for preventing and treating bone loss is limited.
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Research Article|
July 06 2007
Prevention and Treatment of Bone Loss After a Spinal Cord Injury: A Systematic Review
Maureen Ashe;
Maureen Ashe
1
Rehabilitation Research Lab, GF Strong Rehab Centre, and School of Rehabilitation Sciences, University of British Columbia, British Columbia, Canada.
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Catharine Craven;
Catharine Craven
2
Department of Medicine, Toronto Rehabilitation Institute, Lyndhurst Centre, Universtiy of Toronto, Toronto, Ontario.
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Janice Eng;
Janice Eng
3
School of Rehabilitation Sciences, University of British Columbia; Scientist, Rehabilitation Research Lab, GF Strong Rehab Centre; and Investigator, International Collaboration on Repair Discoveries (ICORD), Vancouver, Canada.
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Andrei Krassioukov
Andrei Krassioukov
4
Division of Physical Medicine and Rehabilitation, Faculty of Medicine, University of British Columbia, and Investigator, ICORD, Vancouver, Canada.
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Top Spinal Cord Inj Rehabil (2007) 13 (1): 123–145.
Citation
Maureen Ashe, Catharine Craven, Janice Eng, Andrei Krassioukov; Prevention and Treatment of Bone Loss After a Spinal Cord Injury: A Systematic Review. Top Spinal Cord Inj Rehabil 1 July 2007; 13 (1): 123–145. doi: https://doi.org/10.1310/sci1301-123
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