Pain without clinical evidence of sensation is an ironic but frequent phenomenon. An individual with a spinal cord injury (SCI) is likely to experience many types of painful sensations that can be difficult to categorize, making effective treatment protocols and research studies difficult to design. This chapter will focus on descriptions of nociceptive and neuropathic pain at and below the level of the SCI and will provide basic information about pain mechanisms and diagnostic considerations in their management. Further research is needed to help determine more effective treatments for this problem.

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