A new theoretical tire model for the wear progress of tires with tread block pattern is developed considering a two-dimensional contact patch. In the model, the wear energy is calculated from the shear force and pressure distribution in a two-dimensional contact patch that are changed with not only shear forces in a contact patch but also with the wear and irregular wear of tires. The fore–aft shear force in a contact patch consists of six mechanisms related to slip ratio, camber, contact between a tire and a road, barrel deformation of a loaded block, rolling resistance, and a rolling tire with rounded crown shape, whereas the lateral shear force consists of three mechanisms related to slip angle/camber, contact of a tire with rounded crown shape, and barrel deformation of a loaded block. The heel and toe irregular wear and the progress of irregular wear under pure slip condition qualitatively agree with the conventional knowledge of tire engineers. The expected wear energy is introduced to predict the wear progress under combined slip condition in the wear course. Using the vehicle dynamics to predict the tire force history, a histogram of external forces is obtained by transforming from it. Calculating wear energies by changing slip angle and slip ratio, the relation between external forces and the wear energy is expressed as the response surface. Multiplying the wear energy by the histogram, the expected wear energy distribution in a block is calculated. Assuming that the worn depth is proportional to the expected wear energy, the wear progress is predicted.