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TABLE 2:

Psychotropic medications use prescribed prior to admission and at discharge

Psychotropic medications use prescribed prior to admission and at discharge
Psychotropic medications use prescribed prior to admission and at discharge

 

Prior to Admission Medications 

Discharge Medications 

BPD, n = 85 

MDD, n = 80 
Statistical Value 
BPD, n = 85 

MDD, n = 80 
Statistical Value 

95% CI 

95% CI 
Total No. medications 273 169  244 193  
Mean ± SD medications per patient 3.2 ± 2.3 2.1 ± 1.6 .51-1.7a 2.87 ± 1.7 2.35 ± 1.2 .06-.98a 
Mean ± SD medication classes per patient 2.4 ± 1.4 1.7 ± 1.2 .20-.39a 2.33 ± 1.2 1.86 ± .85 .14-.79a 

 

 

 

P Value 

 

 

P Value 
Medication classes: No. of patients prescribed, n (%) 
 Antidepressants 55 (64.7) 59 (73.8) .21 59 (69.4) 76 (95)a <.001a 
 Antipsychotic 40 (47.1) 11 (13.8) <.001a 40 (47.1)a 12 (15) <.001a 
 Miscellaneous agentsb 21 (24.7) 10 (12.5) .05a 14 (16.5) 7 (8.8) .14 
 Mood stabilizers 32 (37.6) 9 (11.3) <.001a 33 (38.8) 9 (11.3) <.001a 
 Sedatives 58 (68.2) 43 (53.8) .06 52 (61.2) 45 (56.3) .52 
Medication combinations, n (%) 
 ≥2 Antidepressants 12 (14.1) 13 (16.3) .70 8 (9.4) 23 (28.8) .001a 
 ≥2 Antipsychotics 6 (7.1) 1 (1.3) .06 6 (7.1) 1 (1.3) .06 
 ≥2 Sedatives 32 (37.6) 17 (21.3) .02a 21 (24.7) 12 (15) .12 
 Antidepressant + antipsychotic 30 (35.3) 10 (12.5) .001a 33 (38.8) 12 (15) .001a 
 Antidepressant + mood stabilizer 21 (24.7) 8 (10) .01a 23 (27.1) 8 (10) .005a 
 Antidepressant + sedative 42 (49.4) 40 (50) .94 39 (45.9) 44 (55) .24 

 

Prior to Admission Medications 

Discharge Medications 

BPD, n = 85 

MDD, n = 80 
Statistical Value 
BPD, n = 85 

MDD, n = 80 
Statistical Value 

95% CI 

95% CI 
Total No. medications 273 169  244 193  
Mean ± SD medications per patient 3.2 ± 2.3 2.1 ± 1.6 .51-1.7a 2.87 ± 1.7 2.35 ± 1.2 .06-.98a 
Mean ± SD medication classes per patient 2.4 ± 1.4 1.7 ± 1.2 .20-.39a 2.33 ± 1.2 1.86 ± .85 .14-.79a 

 

 

 

P Value 

 

 

P Value 
Medication classes: No. of patients prescribed, n (%) 
 Antidepressants 55 (64.7) 59 (73.8) .21 59 (69.4) 76 (95)a <.001a 
 Antipsychotic 40 (47.1) 11 (13.8) <.001a 40 (47.1)a 12 (15) <.001a 
 Miscellaneous agentsb 21 (24.7) 10 (12.5) .05a 14 (16.5) 7 (8.8) .14 
 Mood stabilizers 32 (37.6) 9 (11.3) <.001a 33 (38.8) 9 (11.3) <.001a 
 Sedatives 58 (68.2) 43 (53.8) .06 52 (61.2) 45 (56.3) .52 
Medication combinations, n (%) 
 ≥2 Antidepressants 12 (14.1) 13 (16.3) .70 8 (9.4) 23 (28.8) .001a 
 ≥2 Antipsychotics 6 (7.1) 1 (1.3) .06 6 (7.1) 1 (1.3) .06 
 ≥2 Sedatives 32 (37.6) 17 (21.3) .02a 21 (24.7) 12 (15) .12 
 Antidepressant + antipsychotic 30 (35.3) 10 (12.5) .001a 33 (38.8) 12 (15) .001a 
 Antidepressant + mood stabilizer 21 (24.7) 8 (10) .01a 23 (27.1) 8 (10) .005a 
 Antidepressant + sedative 42 (49.4) 40 (50) .94 39 (45.9) 44 (55) .24 

BPD = borderline personality disorder; CI = confidence interval; MDD = major depressive disorder.

a

P < .05, between BPD group and MDD group.

b

Miscellaneous agents included benztropine, buspirone, diphenhydramine, donepezil, hydroxyzine, prazosin, and stimulant medications.

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