mRNA expression levels of APOBEC3H and FDXR (panels A and B, respectively) in blood from radiotherapy patients. Blood samples from 19 patients, comprising those with endometrial, breast, lung, prostate, esophageal and colon cancer, were analyzed. Blood was collected at three time points: before the start of the treatment, at 0.5–2 h and 24 h after the first fraction. Individual data points are shown for all patients, together with the mean ± SD (each patient is represented with a different symbol). Each cancer group was color coded. Statistical analyses were performed in log-transformed data. *Significantly different from the control (before treatment) (paired t test, P ≤ 0.05).