Potential role of LD-RT to combat the cytokine storm in severe pneumonia associated with COVID-19 pulmonary damage. Three potential mechanisms of low-dose radiation are highlighted, acting on different components of the respiratory syndrome. (Published and modified, with permission, from Shi Y, Wang Y, Shao C, Huang J, Gan J, Huang X, et al. COVID-19 infection: the perspectives on immune responses. Cell Death Differ 2020; 27:1451–4.)