Drug tissue residues detected in black bears (Ursus americanus) sedated with butorphanol, azaperone, and medetomidine; antagonized with atipamezole and naltrexone; and then euthanized and sampled at intervals over an 8-d period after immobilization and recovery (where allowed). Liver, kidney, fat, and skeletal muscle tissue samples from each subject were screened. “All” means the respective drug was detected in all four tissues at that time point; otherwise, only the specific tissues listed parenthetically had detectable drug.