Microscopic findings in Lagovirus europaeus GI.2/RHDV2/b (rabbit hemorrhagic disease virus 2)–positive desert cottontails (Sylvilagus audubonii) and black-tailed jackrabbits (Lepus californicus) from Arizona, Texas, and New Mexico, USA, collected in April and May 2020. The number of cases assessed for each lesion varies due to tissue availability and degree of postmortem artifact.