Predominant leukocyte populations for green (Chelonia mydas) turtles from two locations in Florida, USA: the Indian River Lagoon (high prevalence of green turtle fibropapillomatosis [GTFP]; with [VT+] and without [VT–] visible tumors) and the Trident Basin (TRI) where GTFP is rare. Animals were sampled in 1999 and 2001 and from 2011 to 2013 across all seasons. There were no differences in the percentage composition of the leukocytes between turtles from the two locations (P=0.866), except in the monocyte population. *Monocyte levels are significantly higher in TRI turtles than in VT+ (P=0.002). There is no statistical difference (P=0.119) between VT+ turtles and turtles without tumors (VT– and TRI).