FIG. 2
Forest plot and summary of meta-analysis of all studies reporting ERR. This figure shows the meta-analysis of aggregate data using the random-effects inverse-variance model with DerSimonian-Laird estimate of tau2. Each row represents a different point estimate corresponding to the relative risk of disease outcomes from exposure to radiation with 95% confidence intervals. An overall random effects estimate is provided in the last line along with the test statistics. Our meta-analysis shows that the risk of dementia incidence or mortality in populations exposed to over 100 mSv is 1.11 (95% CI: 1.04, 1.18; P=0.001) times the risk in those unirradiated. The width of the diamond represents the overall confidence interval from the meta-analysis and does not contain the null of 1. The heterogeneity present is low with I2=37.1%, with Cochran's Q-test showing a lack of statistical significance at P = 0.133. Abbreviations: D: Dementia; PD: Parkinson's Disease; AD: Alzheimer's Disease; MND: Motor Neuron Diseases; MRW: Medical Radiation Workers; NPP: Nuclear Power Plant; MPS: Million Person Study; IR: Industrial Radiographers.

Forest plot and summary of meta-analysis of all studies reporting ERR. This figure shows the meta-analysis of aggregate data using the random-effects inverse-variance model with DerSimonian-Laird estimate of tau2. Each row represents a different point estimate corresponding to the relative risk of disease outcomes from exposure to radiation with 95% confidence intervals. An overall random effects estimate is provided in the last line along with the test statistics. Our meta-analysis shows that the risk of dementia incidence or mortality in populations exposed to over 100 mSv is 1.11 (95% CI: 1.04, 1.18; P=0.001) times the risk in those unirradiated. The width of the diamond represents the overall confidence interval from the meta-analysis and does not contain the null of 1. The heterogeneity present is low with I2=37.1%, with Cochran's Q-test showing a lack of statistical significance at P = 0.133. Abbreviations: D: Dementia; PD: Parkinson's Disease; AD: Alzheimer's Disease; MND: Motor Neuron Diseases; MRW: Medical Radiation Workers; NPP: Nuclear Power Plant; MPS: Million Person Study; IR: Industrial Radiographers.

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