Figures 1–4. Figure 1. Control group at 4 weeks. New osteoid matrix is present in the periphery of the bone defects (Toluidine blue and acid fuchsin, original magnification ×20). Figure 2. Control group at 4 weeks. Many osteoblasts are present (Toluidine blue and acid fuchsin, original magnification ×400). Figure 3. Test group at 4 weeks. New bone extended also in the central portion of the bone defect (Toluidine blue and acid fuchsin, original magnification ×20). Figure 4. Test group at 4 weeks. Newly formed trabecular bone is present. Emdogain is not any more present (Toluidine blue and acid fuchsin, original magnification ×400)