Figures 4–7. Figure 4 . Photomicrograph showing the mosaic-like arrangements of bone and particles at the mid third, contrasting with a less trabecular pattern in the area adjacent to the defect. The arrow indicates the defect's edge. Figure 5. Photomicrograph of site implanted with BHA(s). (a) The arrow indicates woven bone formation on the granule. (b) The arrow shows a Howship's lacunae indicating bone remodeling. Figure 6. Photomicrograph of foreign body–like multinuclear giant cells in intimate contact with the granule surface of BHA(s). Figure 7. Photomicrograph of the open end of a defect implanted with BHA(s). (a) The cortical bone formed in the defect is shown leveled up at the adjacent cortical bone surface. (b) Control defect showing typical soft tissue invasion.