(A, B) Immediate loading of implants in a posterior mandible with a temporary fixed restoration. (C) There is no evidence of crestal bone loss after 2 years of functional loading. (D) Histological specimen from a monkey that demonstrates excellent healing and bone formation following immediate loading. (E) Histological specimen from a human biopsy shows excellent bone-to-implant integration without fibrous tissue formation at the interface 7 months after immediate loading. (F) Higher magnification demonstrates a mature bone with a high number of osteocytes